Tampa Bay Research Institute's blog

New York Biotech firm will temporarily set up their lab at TBRI

Tampa Bay Research Institute Celebrates 30 Years in Pinellas County

St. Petersburg, Fl – (October 2011) – The 30th Anniversary celebration culminates with a Gala being held on November 3, 2011 at the Carillon Hilton in St. Petersburg.  At this occasion, TBRI will honor Mr. and Mrs. John Galbraith, Mr. Andrew H. Hines Jr., and Ms. Beth Morean for their dedication to TBRI throughout the years. 

Feb 23, 2010: Stephen Daniells reports in the Research Headlines section of Nutra Ingredients-USA.com about the implications of TBRI's latest publication. The title of the article is, Pine cone extract may reduce allergy risk

April 2010: An article describing the beneficial effects of Allera Health Products' Immune Extra, appears in the Science of Supplements section of the April 2010 issue of Vitamin Retailer. click here for online edtion

September 2010: Dr. Bradley, TBRI's senior researcher, was a guest on CBS Radio Tampa Bay with award winning talk journalist John Sipos.

March 4, 2011: Dr. Bradley was the guest on Life Improvement Radio.com's internet radio show, Healthcare Advancements, hosted by Laurie Puckett. (click here to listen to the PODcast of the interview).

The Scientific Advisory Council of the Tampa Bay Research Institute, Inc. (TBRI) releases its annual review.

The Scientific Advisory Council of the Tampa Bay Research Institute, Inc. conducted an annual review of its research and research facilities this past week. The laboratories are located at 10900 Roosevelt Blvd., St. Petersburg, Fl.

During a typical flu season in which we have developed and administered the correct vaccine, approximately 48 million people in the United States become infected, 114,000 require hospitalization, and 35,000 die as a result of complications from the infection. Globally, the flu results in the death of up to 500,000 people each season. The majority of deaths occur in the very young ( 65 yrs old), as members of both age groups have weakened immune systems that have difficulty fighting off the infection.

An WW, Kanazawa Y, Ozawa M, Nakaya K, Saito T, Tanaka A, Bradley WG. Dendritic cell differentiation and tumor cell apoptosis induced by components of a poly-phenylpropanoid polysaccharide complex. Anticancer Res. 2010 Feb;30(2):613-22. PubMed PMID: 20332479.

Summary:

This paper describes the results of collaboration between TBRI and Dr. Kazuyasu Nakaya’s laboratory in Niigata University, Japan. The findings published in this article are an extension of the our first publication (Bradley et al, 2003) that described the ability of the pine cone extract to enhance the development of human dendritic cells, cells critical for the initiation of immune responses against invading pathogens, cancer cells, and vaccines. In this paper we describe the discovery of two distinctive activities within the pine cone extract. The first activity, found to be restricted to a fraction containing rather large molecules, is associated with an ability to induce the generation and maturation of dendritic cells derived from murine bone marrow. The second activity discovered was found to be contained within a fraction consisting of much smaller molecules. The activity in this fraction is associated with the ability to induce programmed cell death (apoptosis) in several human cancer cell lines. This means that the pine cone extract could potentially induce cell death in tumor or infected cells and then activate dendritic cells that could initiate an immune response against the tumor or infection.